HeLa cells were subjected to SDS PAGE followed by western blot with FNab03952(HNRNPF antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab03952(HNRNPF antibody) at dilution of 1:50
Background
Component of the heterogeneous nuclear ribonucleoprotein(hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.